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15 yo, F

Asymptomatic patient


Gross Findings

The specimen consisted of an intact central tooth with a cyst-like tissue associated with the crown and half of the root of the tooth.


Microscopic Findings

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Final Diagnosis:


  • < 5% of odontogenic tumours
  • More than 95% of AOTs are intraosseous
  • Invariably asymptomatic
  • Bony expansion +/-



  • Enucleation
  • Recurrence due to incomplete excision


Take-Home Messages

“Two-thirds” rule:

  • Two-thirds occur in females
  • Two-thirds occur in the maxilla
  • Two-thirds are associated with an impacted tooth
  • Two-thirds of the impacted teeth are canines
  • Two-thirds of the radiographs show radiopaque flecks of calcifications


  • Must be differentiated from solid ameloblastoma due to its significantly different biologic behavior and treatment           

(Practical Head and Neck Pathology, Frequently Asked Questions, 2019)